منابع مشابه
Pineal miRNAs and melatonin synthesis
1 Micro RNAs in the Pineal Gland: mir-483 Regulates Melatonin Synthesis by Targeting Arylalkylamine N-Acetyltransferase Samuel JH Clokie, Pierre Lau, Hyun Hee Kim, Steven L. Coon and David Klein. From the Section on Neuroendocrinology, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Heal...
متن کاملMelatonin; from pineal gland to healthy foods Melatonin; pineal bezden sağlıklı yiyeceklere
Obviously, the human diet has become progressively more divergent from those of our ancestors. This maladaptive change became apparent with the Industrial Revolution and has been accelerating in recent decades. In conjunction with this discordance between our ancient, genetically determined biology and the nutritional pattern, in contemporary Western populations, many of the so-called diseases ...
متن کاملLocally synthesized angiotensin modulates pineal melatonin generation.
We aimed to study the mechanisms and the significance of the influence exerted by the renin-angiotensin system (RAS) on the pineal melatonin production. Pineal melatonin and other indoles were determined by HPLC with electrochemical detection after angiotensin AT1-receptor blockade with Losartan in vivo or in cultured glands. N-acetyltransferase (NAT) activity was radiometricaly measured. To te...
متن کاملMelatonin, the pineal gland, and circadian rhythms.
Amniote circadian organization derives from the interactions of circadian oscillators and photoreceptors located in the hypothalamic suprachiasmatic nuclei (SCN), the pineal gland, and the eyes. In mammals, circadian organization is dominated by the SCN, which serve as "master pacemakers" in the control of a wide array of behavioral and physiological rhythms (including locomotion, sleep-wake, t...
متن کاملThe Immune-Pineal Axis: the Role of Pineal and Extra-Pineal Melatonin in Modulating Inflammation
Participation of the pineal gland and melatonin in the innate immune response is part of a dynamic and intricate network that acts throughout the inflammatory response, integrating signaling pathways and regulatory processes at the molecular, cellular and organism levels. The pineal gland is a target for pathogen-associated molecular patterns and for inflammatory mediators, and melatonin, which...
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ژورنال
عنوان ژورنال: General and Comparative Endocrinology
سال: 1975
ISSN: 0016-6480
DOI: 10.1016/0016-6480(75)90188-4